Cochrane Database Syst Rev 2018;3:CD006897. 3. 2. We applied no language restrictions. Oral vitamin B12 versus intramuscular vitamin B12 for vitamin B12 deficiency. …
Lane L.A., Rojas-Fernandez C. Treatment of vitamin B12 deficiency anemia: oral versus parenteral therapy Ann Pharmacother 2002 ; 36 : 1268-1272 [4] Andrès E., Federici L., Serraj K., Kaltenbach G. Update of nutritient-deficiency anemia in elderly patients Eur J Intern Med 2008 ; 19 : 488-493 Large studies comparing the efficacy of SL vs. IM supplements are lacking. BACKGROUND: Vitamin B(12) deficiency is common, increasing with age. This study investigated the effectiveness, safety, and acceptability of oral vitamin B12 as replacement therapy in patients with vitamin B12 deficiency in a city general practice population. In the long run, however, vitamin B12 deficiency can severely affect your health, as explained below. The aim of the present study was to compare the efficacy of SL versus the standard IM administration of VB12 in restoring B12 levels. 2018 Mar 15;3:CD004655. Author information: (1)Institute of Traditional Chinese Medicine, Beijing University of Chinese Medicine, No. A comment on this article appears in "Review: Limited evidence from 2 randomised controlled trials suggests that oral and intramuscular vitamin B12 have similar effectiveness for vitamin B12 deficiency. However, this may not be enough, so B-12 pills may still be required in certain cases. Oral versus intramuscular cobalamin treatment in megaloblastic anemia: a single-center, prospective, randomized, open-label study. 11, North Third Ring Road, School range, ChaoYang District, Beijing, Beijing, China, 100029.
Most people with vitamin B12 deficiency are treated in primary care with intramuscular vitamin B12 which is a considerable source of work for health care professionals.
and that oral supplements are as effective as injections of vitamin B12. Oral route: 1 mg/day of vitamin B12 for 8 weeks; 1 mg/week from weeks 9–52 Oral vitamin B12 versus intramuscular vitamin B12 for vitamin B12 deficiency. ↵ Castelli MC, Friedman K, Sherry J, Brazzillo K, Genoble L, Bhargava P, et al. The following protocol was designed to compare the effectiveness of orally and intramuscularly administered vitamin B12 in the treatment of patients ≥65 years of age with vitamin B12 deficiency.
Oral vitamin B12 versus intramuscular vitamin B12 for vitamin B12 deficiency. Why Vitamin B12 Is Important for Health Vitamin B12 is a water-soluble vitamin that is naturally produced by bacteria that live in animals.
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